Remodeling of Blood Vessels

Blood Vessels

This excellent monograph by Phillippe Sengel brings together an enormous body of data on the embryonic development of the skin in mammals, birds, and reptiles, and most of the information available on the many chemical factors and tissue interactions which produce these changes. The book is divided into four sections. The first describes the histogenesis of developing skin visible with the ligh...

Regulation of blood vessels.

THE CARDIOVASCULAR system serves the biologic organism as a transportation and mixing system. The demalnd by the organism for this service varies in different tissues and at different times while the volume of blood in the organism tends to remain constant. The cardiovascular system fulfills its function, therefore, by varying the rate and the distribution of blood flow. Blood vessels play a ma...

Mechanics of Blood Vessels

Remodeling of blood vessels: responses of diameter and wall thickness to hemodynamic and metabolic stimuli.

Vascular functions, including tissue perfusion and peripheral resistance, reflect continuous structural adaptation (remodeling) of blood vessels in response to several stimuli. Here, a theoretical model is presented that relates the structural and functional properties of microvascular networks to the adaptive responses of individual segments to hemodynamic and metabolic stimuli. All vessels ar...

Blood flow reprograms lymphatic vessels to blood vessels.

Human vascular malformations cause disease as a result of changes in blood flow and vascular hemodynamic forces. Although the genetic mutations that underlie the formation of many human vascular malformations are known, the extent to which abnormal blood flow can subsequently influence the vascular genetic program and natural history is not. Loss of the SH2 domain-containing leukocyte protein o...